Peptides are among the most effective active ingredients in cosmetology and anti-aging supplements. Thanks to their ability to stimulate collagen synthesis and tissue regeneration, they have become the foundation of modern skin care. In this article, we explain how specific peptides available in the SYNTHAGEN range work and why it is worth including them in your individual strategy for supporting skin firmness and a youthful appearance.
What are peptides and why do they affect the skin?
Peptides are short chains of amino acids with powerful biological effects. Their structure allows them to easily penetrate the skin barrier, enabling them to act directly on the deeper layers of the skin. Many peptides act as a regenerative signal – they trigger repair mechanisms such as:
- collagen production,
- elastin
- hyaluronic acid.

As we age, the amount of collagen in the body decreases, leading to a loss of firmness and the appearance of wrinkles. Peptides can activate fibroblasts, which are responsible for collagen production. What is more, some of them have antioxidant or neuroprotective properties, which support the overall condition of the skin and tissues.
These properties make peptides a key element of anti-aging treatments, both in the form of supplements and topical preparations.
Which peptides best support collagen production?
Not all peptides work the same way – some have a particularly strong effect on collagen synthesis.
The main peptides that support collagen:
- NL-GHK-CU – a copper peptide with powerful regenerative properties
- NL-EPITHALON – supports cell renewal and slows down aging
- NL-BPC-157 – a powerful stimulator of tissue healing and collagen regeneration
NL-GHK-CU
Known for its unique ability to stimulate the production of type I and III collagen. At the same time, it reduces inflammation and promotes wound healing, making it a valuable support for mature and demanding skin.
NL-EPITHALON
It acts at the telomere level, slowing down the aging process and supporting fibroblast efficiency. As a result, the skin becomes more elastic and resistant to damage.
NL-BPC-157
Known mainly for its use in tissue regeneration, it also has a documented effect on collagen and capillary reconstruction, which translates into healthier skin tone and elasticity.
How do peptides improve skin firmness and structure?
Peptides affect firmness by supporting the intercellular matrix. This action primarily involves the activation of fibroblasts, which produce not only collagen, but also elastin and proteoglycans – key components responsible for skin elasticity. Peptides also increase skin hydration and reduce microinflammation, which accelerates aging.
Did you know?
Clinical studies have shown that regular use of peptides can reduce the appearance of wrinkles by up to 30% in just a few weeks. The best results are achieved with systematic supplementation and the use of external preparations. Combined with a proper diet and UV protection, peptides can significantly delay the visible signs of aging, improving facial contours and skin tone.
What other peptides are worth knowing about and how do they work?
In addition to strictly collagen peptides, there are also those that support regeneration and neuroprotective functions.
Additional peptides with supportive effects:
- NL-SELANK – anti-anxiety and stabilizing effects on the nervous system
- NL-SEMAX – supports cognitive functions and increases resistance to oxidative stress
- NL-CORTAGEN – regenerates the nervous system and improves cellular efficiency
Although these peptides do not act directly on collagen, their effect on the body indirectly affects the condition of the skin – by reducing oxidative stress, improving sleep quality, and increasing cellular vitality.
FAQ - frequently asked questions
- Are peptides safe for the skin?
Yes, peptides are natural biological components and are well tolerated by the body. However, it is important to use them in appropriate doses. - Can different peptides be combined?
Yes, many peptides work synergistically. Combining NL-GHK-CU with NL-EPITHALON, for example, can significantly increase the effects of therapy. - Which peptide is best for wrinkles?
NL-GHK-CU is most often recommended due to its direct effect on collagen and skin regeneration.
Discover the full range of SYNTHAGEN peptides and choose the formula that best suits your skin's needs. Take care of your skin's firmness, regeneration, and youthful appearance – without compromise.






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