The use of peptides in skin regeneration after exposure to UV radiation

Ultraviolet (UV) radiation is one of the main factors damaging the skin. Short-term exposure can lead to redness, irritation, or sunburn, while chronic exposure accelerates skin aging, causes loss of elasticity, discoloration, and increases the risk of cancer.

The skin has natural protective mechanisms, such as antioxidants and DNA repair enzymes, but intense or repeated exposure can overwhelm them. This is where peptides—short chains of amino acids that act as chemical signals—play an important role, supporting tissue regeneration, collagen production, and skin cell defense mechanisms.

How UV rays damage the skin

UV radiation is divided into UVA and UVB. UVB is mainly responsible for sunburn, while UVA penetrates deeper, accelerating skin aging by damaging collagen and elastin fibers and forming free radicals, i.e., reactive oxygen species that can destroy cells and accelerate degenerative processes.

Peptides used in skin regeneration

Signal peptides (Palmitoyl Pentapeptide)

Signaling peptides are short chains of amino acids that act as “signals” for skin cells, mainly fibroblasts – cells responsible for the production of collagen, elastin, and other components of the intercellular matrix.

Mechanism of action: A signaling peptide, such as Palmitoyl Pentapeptide, sends a message to fibroblasts that the skin needs to be rebuilt, e.g., after damage caused by UV radiation.

Effects: Accelerates tissue regeneration, promotes healing of micro-injuries, improves skin firmness and elasticity, and helps maintain skin integrity in areas prone to damage.

Benefits for the skin: Reduction of fine lines, improvement of skin density, acceleration of repair processes after sun exposure or mechanical trauma.

Copper peptides (NL-GHK-Cu™)

Copper peptides are a combination of a short peptide and a copper (Cu) ion, which significantly increases their biological activity. NL-GHK-Cu™ is an example of a copper tetrapeptide used in skin regeneration.

Mechanism of action: The GHK tetrapeptide binds to copper and delivers it to skin cells. Copper helps enzymes produce collagen, elastin, and other important skin components, and protects cells from damage. The peptide also stimulates fibroblasts (key to wound healing and maintaining skin integrity) to work, supports the formation of new blood vessels, and accelerates the repair of minor skin damage.

Effects: Faster healing of wounds and micro-injuries, improvement of skin structure, reduction of minor damage caused, for example, by UV radiation.

Benefits for the skin: Increased firmness and elasticity, improved skin tone, accelerated repair processes, and strengthened natural resistance of skin cells to oxidative stress.

Peptydy antyoksydacyjne

Peptydy antyoksydacyjne pełnią funkcję ochronną, neutralizując wolne rodniki i inne reaktywne formy tlenu powstające w skórze podczas stresu oksydacyjnego, promieniowania UV czy zanieczyszczeń środowiskowych.

Mechanizm działania: Działają jako „przekaźniki” sygnalizujące komórkom skóry, aby aktywowały enzymy antyoksydacyjne, które neutralizują wolne rodniki i ograniczają uszkodzenia DNA oraz błon komórkowych.

Efekty: Redukcja stresu oksydacyjnego, zmniejszenie stanów zapalnych i spowolnienie procesów starzenia skóry wywołanego przez wolne rodniki.

Korzyści dla skóry: Ochrona przed fotostarzeniem, spowolnienie utraty kolagenu i elastyny, zmniejszenie zaczerwienień oraz poprawa ogólnej kondycji i wyglądu skóry.

Summary

Peptides, including NL-GHK-Cu™, provide modern support for skin regeneration after exposure to UV radiation. By stimulating collagen production, protecting cells from oxidative stress, reducing inflammation, and improving the skin barrier, they accelerate tissue repair and limit the effects of sun damage. Their use is particularly beneficial for people exposed to the sun, athletes, and those who care about healthy and youthful-looking skin.

FAQ

1. What is NL-GHK-Cu™ and how does it work on the skin?
   NL-GHK-Cu™ is a copper-bound tetrapeptide that stimulates fibroblasts to produce collagen and elastin. It supports the regeneration of microdamage to the skin and improves its firmness and elasticity. In addition, it increases the resistance of cells to oxidative stress, which helps protect the skin from free radicals. Regular use can improve the overall condition and appearance of the skin.
   
   
2. Do peptides work immediately after sun exposure?
   Some effects, such as soothing redness and irritation, may appear fairly quickly after application. However, full tissue regeneration requires systematic use of peptides over a longer period of time. This makes the skin more resistant to damage and improves its regeneration. Regular use strengthens the skin's natural protective mechanisms.
   
   
3. Do peptides replace UV filter creams?
   No – peptides support skin regeneration, but do not protect against UV radiation. Sunscreens are still essential to prevent skin damage and premature aging. Peptides work in a complementary way, helping to rebuild and strengthen tissues after sun exposure. Their use does not exempt you from daily sun protection.
   
   
4. Can peptides be used every day?
   Yes, peptides are safe for regular use and can be part of your daily skincare routine. They support skin regeneration, improve elasticity, and support natural protective mechanisms. Regular use helps keep your skin in good condition and can slow down the signs of aging. However, it is important to use the products as recommended by the manufacturer.